منابع مشابه
More than one way to go.
D ramatic changes accompany the death of cells. Attempts to align these changes into cognate groups and identify the mechanisms responsible for them have led to substantial and sometimes surprising insights into cell biology. One such constellation of structural and functional changes is associated with apoptosis (a death process found in development, atrophy, the targets of cell killing by the...
متن کاملMore than one way to attach
ow cells connect to each other and to the extracellular matrix (ECM) was a sticky issue in the early 1980s. Integrins, molecules that hook the cy-toskeleton to ECM proteins such as collagen and fibronectin, hadn't been discovered, but evidence for a link between external and internal fibers was mounting. For example, Irwin Singer (1979) observed that extra-cellular fibronectin molecules closely...
متن کاملThere's More than One Way
We hooked the 5th wheel and boat to the truck for the 240-mile drive to Salmon Falls Creek Reservoir for a walleye tournament. The reservoir is between Twin Falls, Idaho and Jackpot, Nevada. We always look forward to fishing this tournament as it’s a good walleye fishery and we have a lot of friends in the area. We pulled into the federal camp ground at the lake at noon on June 10 and were look...
متن کاملMore than one way to make a tail.
The vast majority of eukaryotic messenger mRNAs undergo 30 end cleavage and polyadenylation. The noncanonical poly(A) polymerase (PAP), STAR-PAP, adds a poly(A) tail to specific transcripts under oxidative stress conditions. These transcripts have the AAUAAA polyadenylation signal and use the same factors for cleavage, but are not polyadenylated by the canonical polyA polymerase. In this issue ...
متن کاملMore than one way to skin a phagosome
In This Issue In This Issue More than one way to skin a phagosome hagosome studies have rested on a major assumption: that in a given cell, all phagosomes with the same cargo mature alike. On page 185, Henry et al. test this assumption, and find it wanting. Using ratiometric fluorescence microscopy, the authors followed the maturation of individual macrophage phago-somes containing IgG-opsonize...
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ژورنال
عنوان ژورنال: Science
سال: 1995
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.269.5221.154